Mental Health Matters! Dr. Fadwa, Pharm.D., 28 April 202319 May 2024 Mental illnesses such as depression, anxiety, and post-traumatic stress disorder (PTSD) are some of the most debilitating conditions affecting millions of people worldwide. These conditions not only affect one’s mood but also have physical symptoms, including fatigue, muscle weakness, and chronic pain. One potential treatment for mental illness that has gained attention in recent years is the use of collagen activation. Collagen Activation is the most abundant protein in our bodies and is responsible for maintaining healthy skin, hair, nails, and joints. However, recent research has shown that collagen activation may also play a role in supporting mental health. Activation collagen, in particular, is a type of collagen that has been specifically designed to promote brain function and mental health. It contains a unique blend of amino acids, vitamins, and minerals that work together to support cognitive function and reduce symptoms of anxiety and depression. TrueScience Liquid Collagen What’s Inside? Marine Collagen ingredient of liquid collagen Fish Collagen PeptidesResponsibly caught fish, providing peptides from 10 different types of collagens, plus amino acids to support collagen density, elasticity, and moisture for a youthful appearance.* Ruby Quinoa Extract (Chenopodium formosanum)Extract from this grain unlocks the cell’s ability to absorb collagen as it activates natural collagen synthesis to reduce the appearance of fine lines and wrinkles.*Proprietary Berry and Citrus Blend are ingredients in liquid collagen Proprietary Citrus & Berry BlendThese berry and citrus extracts supply vitamin C and antioxidants to promote collagen and elastin production and help your skin create more of its own natural moisture for a healthy, glowing complexion.*Appleberry flavor makes liquid collagen taste great Appleberry FlavorNatural apple, cranberry, raspberry, and strawberry flavors, with no added sugar or artificial sweeteners. Increased activation of the SOD gene up to 27 times to produce antioxidants that can help defend skin cells from oxidative stress.* Upregulated epidermal barrier structure genes (TGM1, KRT1, KRT10) by up to 5 times to support skin’s strength and resilience.* The upregulated gene provides instructions on how to make parts of Type I collagen (COL1A2) by 43% to support collagen production.* The downregulated activity of a gene that produces enzymes responsible for degrading collagen (MMP9) by up to 33% to help maintain collagen you already have .* One of the primary ways that activation collagen works is by improving the communication between brain cells. Studies have shown that activation of collagen can increase the production of neurotransmitters such as dopamine and serotonin, which are responsible for regulating mood, motivation, and overall well-being. In addition to improving neurotransmitter function, the activation of collagen also supports the health of the brain itself. It contains amino acids that are essential for the growth and repair of brain cells, which can help to protect against age-related cognitive decline. But how exactly does the activation of collagen impact mental health? One theory is that collagen may help to reduce inflammation in the brain. Chronic inflammation has been linked to a variety of mental health conditions, including depression and anxiety. By reducing inflammation, collagen may help to alleviate some of the symptoms of these conditions. Clinical evidence: nih.gov: Collagen Mental Health TrueScience. True Results. Clinical trials on key ingredients showed improvements after 8 weeks: Increased collagen density by 42%* Increased catalase (antioxidant) by 202%* Increased skin moisture by 18%* Increased brightness by 5%* Increased smoothness by 10%* Decreased depth of crow’s feet by 22%* Improved appearance of pores and spots by 10%* * Individual results will vary A cell-culture study on red quinoa revealed how this ingredient works to help support healthy skin, collagen may also help to improve gut health, which is closely linked to mental health. The gut-brain axis is a complex communication network between the gut and the brain, and disruptions in this system have been linked to a range of mental health conditions. Collagen can help to repair the gut lining, which may improve gut health and reduce inflammation throughout the body. In conclusion, activation collagen shows promise as a potential treatment for mental illness. While more research is needed to fully understand the mechanisms behind its effects, preliminary studies suggest that it may be a safe and effective way to support brain function and mental health. If you’re struggling with a mental health condition, I’m here to help you! Blog